Gramd2b | GRAM domain containing 2B

GeneMGI:1914815Synonyms: 9130427A09Rik, 9030613F08Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Vision/eye Hematopoietic system Behavior/neurological

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



hyperactivity	4 supporting datasets	Gramd2b^em1(IMPC)J	homozygote	Early adult	3.07x10^-5
abnormal lens morphology	1 supporting dataset	Gramd2b^em1(IMPC)J	homozygote	Late adult	9.63x10^-5
abnormal coat/ hair morphology	1 supporting dataset	Gramd2b^em1(IMPC)J	homozygote	Late adult	5.94x10^-7
impaired glucose tolerance	1 supporting dataset	Gramd2b^em1(IMPC)J	homozygote	Early adult	2.34x10^-5
limb grasping	1 supporting dataset	Gramd2b^em1(IMPC)J	homozygote	Late adult	4.06x10^-5
increased mean corpuscular hemoglobin	1 supporting dataset	Gramd2b^em1(IMPC)J	homozygote	Early adult	6.15x10^-6
impaired righting response	1 supporting dataset	Gramd2b^em1(IMPC)J	homozygote	Late adult	8.82x10^-5
increased mean corpuscular volume	1 supporting dataset	Gramd2b^em1(IMPC)J	homozygote	Early adult	2.64x10^-10
abnormal coat/hair pigmentation	1 supporting dataset	Gramd2b^em1(IMPC)J	homozygote	Late adult	5.34x10^-5
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Gramd2b^em1(IMPC)J	homozygote	Early adult	2x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gramd2b.

Associated images

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Histopathology

There is no histopathology data found for Gramd2b.

IMPC related publications

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External links

No external links available for Gramd2b.

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*Gramd2b^em1(IMPC)J*	Exon Deletion	‌	mouse
*Gramd2b^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Gramd2b^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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