Ppfibp1 | PTPRF interacting protein, binding protein 1 (liprin beta 1)

Physiological systems

3 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

1 No significant impact

21 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetPpfibp1em1(IMPC)JhomozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance2 supporting datasetsPpfibp1em1(IMPC)JhomozygoteEarly adultN/A * 
decreased locomotor activity1 supporting datasetPpfibp1em1(IMPC)JheterozygoteEarly adult6.99x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ppfibp1em1(IMPC)JExon Deletionmouse
Ppfibp1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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