Fgfr1op2 | FGFR1 oncogene partner 2
Physiological systems
22 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Embryo Growth/size/body region Digestive/alimentary Limbs/digits/tail Vision/eye Mortality/aging Cardiovascular system Craniofacial
12 No significant impact
2 Not tested
Data collections
Gene metrics:17Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal tail morphology | 1 supporting dataset | Fgfr1op2em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
embryonic growth retardation | 1 supporting dataset | Fgfr1op2em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
abnormal skin morphology | 1 supporting dataset | Fgfr1op2em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
edema | 1 supporting dataset | Fgfr1op2em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
abnormal placenta vasculature | 1 supporting dataset | Fgfr1op2em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
abnormal retina morphology | 1 supporting dataset | Fgfr1op2em1(IMPC)Mbp | heterozygote | Early adult | 2.3x10-5 | ||
abnormal placenta morphology | 1 supporting dataset | Fgfr1op2em1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
cleft palate | 1 supporting dataset | Fgfr1op2em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
abnormal placenta size | 1 supporting dataset | Fgfr1op2em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
cataract | 1 supporting dataset | Fgfr1op2em1(IMPC)Mbp | heterozygote | Early adult | 6.35x10-5 |
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Human diseases caused by Fgfr1op2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Fgfr1op2.
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Fgfr1op2em1(IMPC)Mbp | Exon Deletion | | mouse |
Fgfr1op2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |