Fgfr1op2 | FGFR1 oncogene partner 2

GeneMGI:1914779Synonyms: 1500031J01Rik

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Embryo Growth/size/body region Digestive/alimentary Limbs/digits/tail Vision/eye Mortality/aging Cardiovascular system Craniofacial

12 No significant impact

2 Not tested

Gene metrics:17Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal tail morphology1 supporting datasetFgfr1op2em1(IMPC)MbphomozygoteE15.5N/A * 
embryonic growth retardation1 supporting datasetFgfr1op2em1(IMPC)MbphomozygoteE15.5N/A * 
abnormal skin morphology1 supporting datasetFgfr1op2em1(IMPC)MbpheterozygoteEarly adultN/A * 
edema1 supporting datasetFgfr1op2em1(IMPC)MbphomozygoteE15.5N/A * 
abnormal placenta vasculature1 supporting datasetFgfr1op2em1(IMPC)MbphomozygoteE15.5N/A * 
abnormal retina morphology1 supporting datasetFgfr1op2em1(IMPC)MbpheterozygoteEarly adult2.3x10-5 
abnormal placenta morphology1 supporting datasetFgfr1op2em1(IMPC)MbpheterozygoteE15.5N/A * 
cleft palate1 supporting datasetFgfr1op2em1(IMPC)MbphomozygoteE15.5N/A * 
abnormal placenta size1 supporting datasetFgfr1op2em1(IMPC)MbphomozygoteE15.5N/A * 
cataract1 supporting datasetFgfr1op2em1(IMPC)MbpheterozygoteEarly adult6.35x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fgfr1op2em1(IMPC)MbpExon Deletionmouse
Fgfr1op2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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