Ergic2 | ERGIC and golgi 2
Physiological systems
21 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Growth/size/body region Limbs/digits/tail Skeleton Cardiovascular system Mortality/aging
13 No significant impact
3 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal seminal vesicle morphology | 1 supporting dataset | Ergic2em1(IMPC)Hmgu | heterozygote | Early adult | N/A * | ||
| increased circulating iron level | 1 supporting dataset | Ergic2em1(IMPC)Hmgu | heterozygote | Early adult | 4.28x10-7 | ||
| long tibia | 1 supporting dataset | Ergic2em1(IMPC)Hmgu | heterozygote | Early adult | 2.11x10-5 | ||
| increased heart weight | 1 supporting dataset | Ergic2em1(IMPC)Hmgu | heterozygote | Early adult | 5.49x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Ergic2em1(IMPC)Hmgu | homozygote | Early adult | N/A * |
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Human diseases caused by Ergic2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Ergic2.
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| Ergic2em1(IMPC)Hmgu | Exon Deletion | | mouse |
| Ergic2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ergic2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |