Myo1h | myosin 1H

GeneMGI:1914674Synonyms: 4631401O15Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Mortality/aging Renal/urinary system

15 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

abnormal embryo size1 supporting datasetMyo1htm1b(KOMP)WtsihomozygoteE18.5N/A * 
embryonic growth retardation1 supporting datasetMyo1htm1b(KOMP)WtsihomozygoteE18.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetMyo1htm1b(KOMP)WtsihomozygoteEarly adultN/A * 
decreased urine magnesium level1 supporting datasetMyo1htm1b(KOMP)WtsiheterozygoteEarly adult5.43x10-5 
abnormal motor coordination/balance1 supporting datasetMyo1htm1b(KOMP)WtsiheterozygoteEarly adult4.98x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Myo1htm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Myo1htm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Myo1htm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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