Brd3 | bromodomain containing 3

GeneMGI:1914632Synonyms: 2410084F24Rik, Fsrg2, +2 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Pigmentation Integument Behavior/neurological Cardiovascular system Mortality/aging

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



prolonged RR interval	1 supporting dataset	Brd3^em1(IMPC)J	homozygote	Early adult	3.67x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Brd3^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased grip strength	1 supporting dataset	Brd3^em1(IMPC)J	homozygote	Early adult	1.06x10^-5
abnormal coat/hair pigmentation	1 supporting dataset	Brd3^em1(IMPC)J	homozygote	Early adult	3.85x10^-5
decreased locomotor activity	1 supporting dataset	Brd3^em1(IMPC)J	homozygote	Early adult	4.17x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Brd3.

Associated images

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Histopathology

There is no histopathology data found for Brd3.

IMPC related publications

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External links

No external links available for Brd3.

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*Brd3^em1(IMPC)J*	Exon Deletion	‌	mouse
*Brd3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Brd3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Brd3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Brd3^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Brd3^{tm34188(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Brd3^{tm3a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Brd3^{tm3e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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