Ndufa10 | NADH:ubiquinone oxidoreductase subunit A10

GeneMGI:1914523Synonyms: 2900053E13Rik

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Adipose tissue Behavior/neurological Skeleton Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased total body fat amount	2 supporting datasets	Ndufa10^{tm1e.1(EUCOMM)Hmgu}	heterozygote	Early adult	6.15x10^-8
abnormal bone structure	1 supporting dataset	Ndufa10^{tm1e.1(EUCOMM)Hmgu}	heterozygote	Early adult	2.06x10^-9
preweaning lethality, complete penetrance	1 supporting dataset	Ndufa10^{tm1e.1(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal gait	1 supporting dataset	Ndufa10^{tm1e.1(EUCOMM)Hmgu}	heterozygote	Early adult	8.82x10^-6
decreased bone mineral density	1 supporting dataset	Ndufa10^{tm1e.1(EUCOMM)Hmgu}	heterozygote	Early adult	3.31x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ndufa10.

Associated images

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Histopathology

There is no histopathology data found for Ndufa10.

IMPC related publications

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External links

No external links available for Ndufa10.

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*Ndufa10^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ndufa10^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell mouse
*Ndufa10^{tm1e.1(EUCOMM)Hmgu}*	Promoter excision from Targeted, non-conditional allele	‌	mouse
*Ndufa10^{tm55415(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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