Med18 | mediator complex subunit 18
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Immune system Hematopoietic system Behavior/neurological Mortality/aging
16 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal behavior | 3 supporting datasets | Med18tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.7x10-14 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Med18tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| decreased leukocyte cell number | 1 supporting dataset | Med18tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 9.53x10-7 |
| | | | | | | | | | |
External links
No external links available for Med18.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Med18tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Med18tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Med18tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Med18tm46343(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |