Ccdc25 | coiled-coil domain containing 25

GeneMGI:1914429Synonyms: 2610528H13Rik

Physiological systems

22 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Embryo Growth/size/body region Nervous system Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging

11 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal vitreous body morphology	1 supporting dataset	Ccdc25^em1(IMPC)Mbp	heterozygote	Early adult	1.63x10^-5
impaired glucose tolerance	1 supporting dataset	Ccdc25^em1(IMPC)Mbp	heterozygote	Early adult	5.16x10^-8
abnormal placenta morphology	1 supporting dataset	Ccdc25^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
abnormal liver morphology	1 supporting dataset	Ccdc25^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
preweaning lethality, incomplete penetrance	1 supporting dataset	Ccdc25^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small spleen	2 supporting datasets	Ccdc25^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
no spontaneous movement	1 supporting dataset	Ccdc25^em1(IMPC)Mbp	heterozygote	E18.5	N/A ^*
cataract	1 supporting dataset	Ccdc25^em1(IMPC)Mbp	heterozygote	Early adult	1.36x10^-5
enlarged heart	1 supporting dataset	Ccdc25^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal retina morphology	1 supporting dataset	Ccdc25^em1(IMPC)Mbp	heterozygote	Early adult	5.03x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ccdc25.

Associated images

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Histopathology

There is no histopathology data found for Ccdc25.

IMPC related publications

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External links

No external links available for Ccdc25.

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*Ccdc25^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Ccdc25^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ccdc25^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ccdc25^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Ccdc25^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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