Ramac | RNA guanine-7 methyltransferase activating subunit

GeneMGI:1914398Synonyms: Fam103a1, 2610204K14Rik, +2 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength2 supporting datasetsRamacem1(IMPC)JheterozygoteEarly adult1.07x10-5 
preweaning lethality, complete penetrance3 supporting datasetsRamacem1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Ramacem1(IMPC)JExon Deletionmouse
Ramactm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ramactm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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