Ndufa6 | NADH:ubiquinone oxidoreductase subunit A6
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Mortality/aging Cardiovascular system
17 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased heart rate | 1 supporting dataset | Ndufa6em1(IMPC)Bay | heterozygote | Early adult | 2.33x10-5 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Ndufa6em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| thick ventricular wall | 1 supporting dataset | Ndufa6em1(IMPC)Bay | heterozygote | Early adult | 3.68x10-5 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Ndufa6em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| prolonged RR interval | 1 supporting dataset | Ndufa6em1(IMPC)Bay | heterozygote | Early adult | 1.05x10-6 |
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External links
No external links available for Ndufa6.
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| Ndufa6em1(IMPC)Bay | Exon Deletion | | mouse |
| Ndufa6tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ndufa6tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |