Ube2g1 | ubiquitin-conjugating enzyme E2G 1

GeneMGI:1914378Synonyms: 2700059C12Rik, D130023C12Rik

Physiological systems

13 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Reproductive system Limbs/digits/tail Hearing/vestibular/ear Liver/biliary system Skeleton

8 No significant impact

11 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:152Adult tissues

25Embryo tissues

Phenotypes

Phy. System:



abnormal auditory brainstem response	3 supporting datasets	Ube2g1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.48x10^-6
vertebral fusion	1 supporting dataset	Ube2g1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.6x10^-7
short tibia	1 supporting dataset	Ube2g1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.03x10^-7
male infertility	1 supporting dataset	Ube2g1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal joint morphology	1 supporting dataset	Ube2g1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.72x10^-5
small liver	1 supporting dataset	Ube2g1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal pelvic girdle bone morphology	1 supporting dataset	Ube2g1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.96x10^-7
fusion of vertebral arches	1 supporting dataset	Ube2g1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.7x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ube2g1.

Associated images

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Histopathology

There is no histopathology data found for Ube2g1.

IMPC related publications

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External links

No external links available for Ube2g1.

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*Ube2g1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ube2g1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ube2g1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ube2g1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Ube2g1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Ube2g1^{tm39131(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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