Ptgr1 | prostaglandin reductase 1

GeneMGI:1914353Synonyms: Zadh3, Ltb4dh, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Skeleton

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lean body mass	1 supporting dataset	Ptgr1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.27x10^-5
decreased bone mineral content	1 supporting dataset	Ptgr1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.03x10^-6
increased total body fat amount	1 supporting dataset	Ptgr1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.35x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ptgr1.

Associated images

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Histopathology

There is no histopathology data found for Ptgr1.

IMPC related publications

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External links

No external links available for Ptgr1.

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*Ptgr1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ptgr1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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