Lsm14a | LSM14A mRNA processing body assembly factor

GeneMGI:1914320Synonyms: Tral, 2700023B17Rik

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Hearing/vestibular/ear Hematopoietic system

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased basophil cell number1 supporting datasetLsm14atm1b(KOMP)WtsiheterozygoteEarly adult2.04x10-6 
decreased erythrocyte cell number1 supporting datasetLsm14atm1b(KOMP)WtsiheterozygoteEarly adult1.19x10-6 
decreased hemoglobin content1 supporting datasetLsm14atm1b(KOMP)WtsiheterozygoteEarly adult8.43x10-7 
abnormal auditory brainstem response1 supporting datasetLsm14atm1b(KOMP)WtsiheterozygoteEarly adult1.37x10-5 
decreased hematocrit1 supporting datasetLsm14atm1b(KOMP)WtsiheterozygoteEarly adult9.76x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lsm14atm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Lsm14atm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Lsm14atm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Lsm14atm37394(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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