Tm9sf3 | transmembrane 9 superfamily member 3

GeneMGI:1914262Synonyms: Smbp, 2810031D16Rik, +1 more

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Integument Embryo Growth/size/body region Mortality/aging

16 No significant impact

2 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/hair pigmentation1 supporting datasetTm9sf3em1(IMPC)MbpheterozygoteEarly adult2.72x10-5 
embryonic growth retardation1 supporting datasetTm9sf3em1(IMPC)MbphomozygoteE15.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsTm9sf3em1(IMPC)MbphomozygoteEarly adultN/A * 
edema1 supporting datasetTm9sf3em1(IMPC)MbphomozygoteE15.5N/A * 
increased circulating phosphate level1 supporting datasetTm9sf3em1(IMPC)MbpheterozygoteEarly adult3.44x10-6 
increased circulating triglyceride level1 supporting datasetTm9sf3em1(IMPC)MbpheterozygoteEarly adult1.45x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tm9sf3em1(IMPC)MbpExon Deletionmouse
Tm9sf3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tm9sf3tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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