Yae1d1 | Yae1 domain containing 1

GeneMGI:1914258Synonyms: 1600012F09Rik

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Nervous system Vision/eye Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating lipase level1 supporting datasetYae1d1tm1b(EUCOMM)HmguheterozygoteEarly adult6.03x10-6 
increased circulating alkaline phosphatase level1 supporting datasetYae1d1tm1b(EUCOMM)HmguheterozygoteEarly adult1.93x10-5 
abnormal lens morphology4 supporting datasetsYae1d1tm1b(EUCOMM)HmguheterozygoteEarly adult2.29x10-7 
preweaning lethality, complete penetrance1 supporting datasetYae1d1tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
increased circulating cholesterol level1 supporting datasetYae1d1tm1b(EUCOMM)HmguheterozygoteEarly adult2.16x10-6 
cataract1 supporting datasetYae1d1tm1b(EUCOMM)HmguheterozygoteEarly adult3.22x10-7 
increased circulating HDL cholesterol level1 supporting datasetYae1d1tm1b(EUCOMM)HmguheterozygoteEarly adult5.1x10-5 
decreased prepulse inhibition1 supporting datasetYae1d1tm1b(EUCOMM)HmguheterozygoteEarly adult8.29x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Yae1d1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Yae1d1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse

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