Rrp8 | ribosomal RNA processing 8
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Mortality/aging
14 No significant impact
5 Not tested
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
50Embryo tissues
| decreased coping response | 1 supporting dataset | Rrp8tm1.1(KOMP)Vlcg | heterozygote | Early adult | 9.16x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Rrp8tm1.1(KOMP)Vlcg | homozygote | E18.5 | N/A * | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Rrp8tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.56x10-6 | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Rrp8tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.77x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Rrp8tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| increased circulating chloride level | 1 supporting dataset | Rrp8tm1.1(KOMP)Vlcg | heterozygote | Early adult | 4.33x10-9 | ||
| embryonic growth retardation | 1 supporting dataset | Rrp8tm1.1(KOMP)Vlcg | homozygote | E18.5 | N/A * |
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External links
No external links available for Rrp8.
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| Rrp8tm1(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Rrp8tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Rrp8tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Rrp8tm442403(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |