Ctu2 | cytosolic thiouridylase subunit 2

GeneMGI:1914215Synonyms: 2310061F22Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Hematopoietic system Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased eosinophil cell number	2 supporting datasets	Ctu2^{tm1(KOMP)Wtsi}	heterozygote	Early adult	1.21x10^-8
increased basophil cell number	2 supporting datasets	Ctu2^{tm1(KOMP)Wtsi}	heterozygote	Early adult	4.67x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Ctu2^{tm1(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ctu2.

Associated images

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Histopathology

There is no histopathology data found for Ctu2.

IMPC related publications

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External links

No external links available for Ctu2.

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*Ctu2^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Ctu2^{tm455762(L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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