Ddx18 | DEAD box helicase 18
Physiological systems
16 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Embryo Growth/size/body region Mortality/aging
13 No significant impact
8 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Ddx18em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Ddx18em1(IMPC)Bay | heterozygote | E9.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Ddx18em1(IMPC)Bay | heterozygote | E9.5 | N/A * |
| | | | | | | | | | |
Human diseases caused by Ddx18 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Ddx18.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Ddx18em1(IMPC)Bay | Exon Deletion | | mouse |
| Ddx18tm47777(pL1L2_GT1_DelLacZ_bsd) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |