Riok3 | RIO kinase 3
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Reproductive system Vision/eye Behavior/neurological
14 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| persistence of hyaloid vascular system | 1 supporting dataset | Riok3em1(IMPC)Mbp | homozygote | Early adult | 1.91x10-5 | ||
| increased vertical activity | 1 supporting dataset | Riok3em1(IMPC)Mbp | homozygote | Early adult | 3.15x10-5 | ||
| abnormal eye morphology | 1 supporting dataset | Riok3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| male infertility | 1 supporting dataset | Riok3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| anophthalmia | 1 supporting dataset | Riok3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased startle reflex | 1 supporting dataset | Riok3em1(IMPC)Mbp | homozygote | Early adult | 6.27x10-5 |
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Human diseases caused by Riok3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Riok3.
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| Riok3em1(IMPC)Mbp | Exon Deletion | | mouse |
| Riok3tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Riok3tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |