Dnajc10 | DnaJ heat shock protein family (Hsp40) member C10

GeneMGI:1914111Synonyms: ERdj5, D2Ertd706e, +2 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating cholesterol level1 supporting datasetDnajc10tm1a(EUCOMM)HmguhomozygoteEarly adult4.39x10-5 
increased mean corpuscular hemoglobin concentration1 supporting datasetDnajc10tm1a(EUCOMM)HmguhomozygoteEarly adult7.55x10-6 
decreased erythrocyte cell number1 supporting datasetDnajc10tm1a(EUCOMM)HmguhomozygoteEarly adult6.59x10-5 
decreased circulating HDL cholesterol level1 supporting datasetDnajc10tm1a(EUCOMM)HmguhomozygoteEarly adult1.23x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dnajc10tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Dnajc10tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Dnajc10tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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