Fbxo25 | F-box protein 25

GeneMGI:1914072Synonyms: 9130015I06Rik, Fbx25

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Renal/urinary system

12 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:16Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal thymus morphology1 supporting datasetFbxo25em1(IMPC)CcpczhomozygoteEarly adultN/A * 
decreased thigmotaxis2 supporting datasetsFbxo25em1(IMPC)CcpczhomozygoteEarly adult7.73x10-5 
abnormal urinary bladder morphology1 supporting datasetFbxo25em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetFbxo25em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetFbxo25em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetFbxo25em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged urinary bladder1 supporting datasetFbxo25em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal vertebral arch morphology1 supporting datasetFbxo25em1(IMPC)CcpczhomozygoteEarly adult7.53x10-5 
decreased mean platelet volume1 supporting datasetFbxo25em1(IMPC)CcpczhomozygoteEarly adult6.31x10-5 
enlarged thymus1 supporting datasetFbxo25em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fbxo25em1(IMPC)CcpczExon Deletionmouse

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