Ube2w | ubiquitin-conjugating enzyme E2W (putative)

GeneMGI:1914049Synonyms: 6130401J04Rik

Physiological systems

15 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hearing/vestibular/ear Behavior/neurological

12 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal auditory brainstem response2 supporting datasetsUbe2wtm1b(EUCOMM)WtsihomozygoteEarly adult3.36x10-6 
increased grip strength1 supporting datasetUbe2wtm1b(EUCOMM)WtsihomozygoteEarly adult7.61x10-6 
increased fasting circulating glucose level1 supporting datasetUbe2wtm1b(EUCOMM)WtsihomozygoteEarly adult6.79x10-13 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ube2wtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ube2wtm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ube2wtm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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