Spryd4 | SPRY domain containing 4

GeneMGI:1913951Synonyms: 4633402N23Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Cardiovascular system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased fasting circulating glucose level1 supporting datasetSpryd4em1(IMPC)CcpczhomozygoteEarly adult4.6x10-5 
abnormal thymus morphology1 supporting datasetSpryd4em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetSpryd4em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetSpryd4em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetSpryd4em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Spryd4em1(IMPC)CcpczExon Deletionmouse
Spryd4tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Spryd4tm464404(L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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