Golph3 | golgi phosphoprotein 3

GeneMGI:1913879Synonyms: 4733401N08Rik, 5730410D03Rik

Physiological systems

18 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Integument Limbs/digits/tail Hearing/vestibular/ear Hematopoietic system Behavior/neurological Skeleton Craniofacial Mortality/aging

6 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal skin morphology	1 supporting dataset	Golph3^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Golph3^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Golph3^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased mean platelet volume	1 supporting dataset	Golph3^em1(IMPC)Tcp	homozygote	Early adult	9.9x10^-5
abnormal forelimb morphology	1 supporting dataset	Golph3^em1(IMPC)Tcp	homozygote	Early adult	9x10^-6
enlarged lymph nodes	1 supporting dataset	Golph3^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
preweaning lethality, incomplete penetrance	1 supporting dataset	Golph3^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
small seminal vesicle	1 supporting dataset	Golph3^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased grip strength	2 supporting datasets	Golph3^em1(IMPC)Tcp	homozygote	Early adult	1.27x10^-9
decreased bone mineral content	2 supporting datasets	Golph3^em1(IMPC)Tcp	homozygote	Early adult	6.02x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Golph3.

Associated images

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Histopathology

There is no histopathology data found for Golph3.

IMPC related publications

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External links

No external links available for Golph3.

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*Golph3^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Golph3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Golph3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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