Snrnp27 | small nuclear ribonucleoprotein 27 (U4/U6.U5)
Physiological systems
21 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Digestive/alimentary Vision/eye Behavior/neurological Mortality/aging
17 No significant impact
3 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
0Embryo tissues
| abnormal esophagus morphology | 1 supporting dataset | Snrnp27tm1b(EUCOMM)Wtsi | heterozygote | Early adult | N/A * | ||
| abnormal retina morphology | 1 supporting dataset | Snrnp27tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 3.35x10-5 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Snrnp27tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Snrnp27tm1b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * | ||
| hyperactivity | 2 supporting datasets | Snrnp27tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 3.3x10-8 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Snrnp27tm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * |
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External links
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| Snrnp27tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Snrnp27tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Snrnp27tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |