Gpatch4 | G patch domain containing 4

GeneMGI:1913864Synonyms: Gpatc4, 2610029K21Rik

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Pigmentation Integument Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small spleen	1 supporting dataset	Gpatch4^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased fasting circulating glucose level	1 supporting dataset	Gpatch4^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.91x10^-6
increased freezing behavior	1 supporting dataset	Gpatch4^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.73x10^-8
abnormal coat/hair pigmentation	1 supporting dataset	Gpatch4^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.08x10^-5
abnormal spleen morphology	1 supporting dataset	Gpatch4^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Gpatch4^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased mean corpuscular hemoglobin	1 supporting dataset	Gpatch4^{em1(IMPC)Ccpcz}	homozygote	Early adult	8.72x10^-5
small seminal vesicle	1 supporting dataset	Gpatch4^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased lean body mass	2 supporting datasets	Gpatch4^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.43x10^-5
decreased CD8-positive, alpha-beta T cell number	1 supporting dataset	Gpatch4^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.41x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gpatch4.

Associated images

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Histopathology

There is no histopathology data found for Gpatch4.

IMPC related publications

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External links

No external links available for Gpatch4.

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*Gpatch4^{em1(IMPC)Ccpcz}*	Inter-exon deletion	‌	mouse
*Gpatch4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Gpatch4^{tm3(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Gpatch4^{tm464003(L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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