Cmpk1 | cytidine/uridine monophosphate kinase 1

GeneMGI:1913838Synonyms: Cmpk, 0610011D08Rik

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Cardiovascular system Mortality/aging Renal/urinary system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



polycystic kidney	1 supporting dataset	Cmpk1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Cmpk1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal retina vasculature morphology	1 supporting dataset	Cmpk1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.98x10^-5
increased circulating iron level	1 supporting dataset	Cmpk1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	9.3x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Cmpk1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.61x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cmpk1.

Associated images

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Histopathology

There is no histopathology data found for Cmpk1.

IMPC related publications

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External links

No external links available for Cmpk1.

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*Cmpk1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Cmpk1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cmpk1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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