Cul7 | cullin 7

GeneMGI:1913765Synonyms: p185, 2510004L20Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Cul7^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased circulating HDL cholesterol level	1 supporting dataset	Cul7^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.39x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cul7.

Associated images

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Histopathology

There is no histopathology data found for Cul7.

IMPC related publications

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External links

No external links available for Cul7.

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*Cul7^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse

My Genes