Nmnat1 | nicotinamide nucleotide adenylyltransferase 1

GeneMGI:1913704Synonyms: 5730441G13Rik, D4Cole1e, +3 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Skeleton

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular volume1 supporting datasetNmnat1tm1a(EUCOMM)WtsiheterozygoteEarly adult1.57x10-7 
abnormal bone structure1 supporting datasetNmnat1tm1a(EUCOMM)WtsiheterozygoteEarly adult1.35x10-5 
increased bone mineral content1 supporting datasetNmnat1tm1a(EUCOMM)WtsiheterozygoteEarly adult1.55x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nmnat1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Nmnat1tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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