Arrdc4 | arrestin domain containing 4
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Immune system Growth/size/body region Hematopoietic system Renal/urinary system
14 No significant impact
6 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased monocyte cell number | 2 supporting datasets | Arrdc4em1(IMPC)Tcp | homozygote | Early adult | 2.12x10-10 | ||
| enlarged lymph nodes | 1 supporting dataset | Arrdc4em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| increased red blood cell distribution width | 1 supporting dataset | Arrdc4em1(IMPC)Tcp | homozygote | Early adult | 3.55x10-8 | ||
| enlarged urinary bladder | 1 supporting dataset | Arrdc4em1(IMPC)Tcp | homozygote | Early adult | N/A * |
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Human diseases caused by Arrdc4 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Arrdc4.
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| Arrdc4em1(IMPC)Tcp | Inter-exon deletion | | mouse |
| Arrdc4tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Arrdc4tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Arrdc4tm47487(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |