Aptx | aprataxin
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Skeleton
14 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| persistence of hyaloid vascular system | 1 supporting dataset | Aptxtm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.23x10-7 | ||
| decreased bone mineral density | 1 supporting dataset | Aptxtm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.45x10-5 | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Aptxtm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.2x10-8 | ||
| decreased bone mineral content | 2 supporting datasets | Aptxtm1b(EUCOMM)Hmgu | homozygote | Early adult | 8.95x10-7 | ||
| cataract | 1 supporting dataset | Aptxtm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.64x10-6 |
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External links
No external links available for Aptx.
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| Aptxtm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Aptxtm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Aptxtm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Aptxtm368(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |