Dus2 | dihydrouridine synthase 2

GeneMGI:1913619Synonyms: Dus2l, 2310016K04Rik

Physiological systems

15 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Hematopoietic system

12 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased total body fat amount	1 supporting dataset	Dus2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.45x10^-5
increased lean body mass	1 supporting dataset	Dus2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.81x10^-5
increased red blood cell distribution width	1 supporting dataset	Dus2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	5.38x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dus2.

Associated images

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Histopathology

There is no histopathology data found for Dus2.

IMPC related publications

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External links

No external links available for Dus2.

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*Dus2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dus2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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