Knop1 | lysine rich nucleolar protein 1

GeneMGI:1913606Synonyms: 2310008H09Rik, Tsg118

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased spleen weight	1 supporting dataset	Knop1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.01x10^-25
increased circulating chloride level	1 supporting dataset	Knop1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.65x10^-7
tremors	1 supporting dataset	Knop1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.46x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Knop1.

Associated images

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Histopathology

There is no histopathology data found for Knop1.

IMPC related publications

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External links

No external links available for Knop1.

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*Knop1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Knop1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Knop1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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