Atp6v1c1 | ATPase, H+ transporting, lysosomal V1 subunit C1
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Nervous system Hematopoietic system Behavior/neurological Mortality/aging
14 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
30Embryo tissues
| increased mean corpuscular volume | 1 supporting dataset | Atp6v1c1tm1b(NCOM)Mfgc | heterozygote | Early adult | 3.86x10-9 | ||
| increased leukocyte cell number | 1 supporting dataset | Atp6v1c1tm1b(NCOM)Mfgc | heterozygote | Early adult | 5.08x10-5 | ||
| decreased prepulse inhibition | 4 supporting datasets | Atp6v1c1tm1b(NCOM)Mfgc | heterozygote | Early adult | 9.5x10-12 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Atp6v1c1tm1b(NCOM)Mfgc | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Atp6v1c1tm1b(NCOM)Mfgc | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Atp6v1c1tm1b(NCOM)Mfgc | homozygote | E12.5 | N/A * | ||
| decreased exploration in new environment | 1 supporting dataset | Atp6v1c1tm1b(NCOM)Mfgc | heterozygote | Early adult | 2.61x10-6 |
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External links
No external links available for Atp6v1c1.
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| Atp6v1c1tm1a(NCOM)Mfgc | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Atp6v1c1tm1b(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | mouse |