Smurf2 | SMAD specific E3 ubiquitin protein ligase 2

GeneMGI:1913563Synonyms: 2810411E22Rik

Physiological systems

8 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

7 No significant impact

16 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes



preweaning lethality, incomplete penetrance	1 supporting dataset		Smurf2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult		N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Smurf2.

Associated images

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Histopathology

There is no histopathology data found for Smurf2.

IMPC related publications

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External links

No external links available for Smurf2.

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*Smurf2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Smurf2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Smurf2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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