Gkn2 | gastrokine 2

GeneMGI:1913534Synonyms: Bricd1b, 1810036H07Rik

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Limbs/digits/tail Nervous system Hematopoietic system Cardiovascular system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased fasting circulating glucose level	1 supporting dataset	Gkn2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	8.29x10^-5
brachydactyly	1 supporting dataset	Gkn2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.26x10^-6
decreased brain weight	1 supporting dataset	Gkn2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.86x10^-7
decreased total body fat amount	1 supporting dataset	Gkn2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.26x10^-5
increased lean body mass	1 supporting dataset	Gkn2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.88x10^-5
enlarged heart	1 supporting dataset	Gkn2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased mean corpuscular volume	1 supporting dataset	Gkn2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.5x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Gkn2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Gkn2.

IMPC related publications

Loading...

External links

No external links available for Gkn2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Gkn2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Gkn2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Gkn2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Gkn2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Gkn2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Gkn2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes