Taf13 | TATA-box binding protein associated factor 13

GeneMGI:1913500Synonyms: 2010309N11Rik, 1810004N01Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength3 supporting datasetsTaf13em1(IMPC)JheterozygoteEarly adult6.24x10-8 
preweaning lethality, complete penetrance1 supporting datasetTaf13em1(IMPC)JhomozygoteEarly adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetTaf13em1(IMPC)JhomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Taf13 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Taf13em1(IMPC)JExon Deletionmouse
Taf13tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Taf13tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Taf13tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Taf13tm404(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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