Sptssb | serine palmitoyltransferase, small subunit B

GeneMGI:1913433Synonyms: ADMP, 1110032A04Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Growth/size/body region Cardiovascular system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

46Embryo tissues

Phenotypes

Phy. System:



decreased circulating iron level	1 supporting dataset	Sptssb^{tm1b(KOMP)Mbp}	homozygote	Early adult	7.94x10^-12
decreased fasting circulating glucose level	1 supporting dataset	Sptssb^{tm1b(KOMP)Mbp}	homozygote	Early adult	5.02x10^-16
increased blood urea nitrogen level	1 supporting dataset	Sptssb^{tm1b(KOMP)Mbp}	homozygote	Early adult	6.15x10^-5
increased fasting circulating glucose level	1 supporting dataset	Sptssb^{tm1b(KOMP)Mbp}	homozygote	Early adult	6.99x10^-5
abnormal coat appearance	1 supporting dataset	Sptssb^{tm1b(KOMP)Mbp}	homozygote	Early adult	2.28x10^-6
decreased circulating glucose level	1 supporting dataset	Sptssb^{tm1b(KOMP)Mbp}	homozygote	Early adult	3.31x10^-6
increased heart weight	1 supporting dataset	Sptssb^{tm1b(KOMP)Mbp}	homozygote	Early adult	4.12x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sptssb.

Associated images

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Histopathology

There is no histopathology data found for Sptssb.

IMPC related publications

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External links

No external links available for Sptssb.

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*Sptssb^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Sptssb^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Sptssb^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Sptssb^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Sptssb^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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