Sptssa | serine palmitoyltransferase, small subunit A
Physiological systems
20 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Mortality/aging
18 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues
| increased circulating sodium level | 1 supporting dataset | Sptssatm1b(KOMP)Wtsi | heterozygote | Early adult | 6.93x10-7 | ||
| decreased circulating glucose level | 1 supporting dataset | Sptssatm1b(KOMP)Wtsi | heterozygote | Early adult | 3.47x10-7 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Sptssatm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Sptssatm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Sptssatm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * |
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External links
No external links available for Sptssa.
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| Sptssatm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Sptssatm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Sptssatm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |