Elof1 | ELF1 homolog, elongation factor 1

GeneMGI:1913376Synonyms: 1110011K10Rik

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological Cardiovascular system Mortality/aging

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to tooth bud stage	1 supporting dataset	Elof1^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
decreased coping response	2 supporting datasets	Elof1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	9.55x10^-6
decreased circulating serum albumin level	1 supporting dataset	Elof1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	4.96x10^-6
increased heart weight	1 supporting dataset	Elof1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	9x10^-5
increased circulating sodium level	1 supporting dataset	Elof1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	8.44x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Elof1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Elof1.

Associated images

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Histopathology

There is no histopathology data found for Elof1.

IMPC related publications

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External links

No external links available for Elof1.

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*Elof1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Elof1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Elof1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Elof1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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