Fkbp11 | FK506 binding protein 11

GeneMGI:1913370Synonyms: 1110002O23Rik

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Nervous system Vision/eye Hematopoietic system

16 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged lymph nodes1 supporting datasetFkbp11em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetFkbp11em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal brain morphology1 supporting datasetFkbp11em1(IMPC)MbphomozygoteEarly adultN/A * 
small spleen1 supporting datasetFkbp11em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetFkbp11em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetFkbp11em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fkbp11em1(IMPC)MbpExon Deletionmouse
Fkbp11tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Fkbp11tm213554(L1L2_Bact_P)Reporter-tagged deletion allele (with selection cassette)targeting vector
Fkbp11tm446430(L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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