Fkbp11 | FK506 binding protein 11
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Immune system Nervous system Vision/eye Hematopoietic system
16 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged lymph nodes | 1 supporting dataset | Fkbp11em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Fkbp11em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal brain morphology | 1 supporting dataset | Fkbp11em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small spleen | 1 supporting dataset | Fkbp11em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal lymph node morphology | 1 supporting dataset | Fkbp11em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Fkbp11em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Fkbp11 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Fkbp11.
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| Fkbp11em1(IMPC)Mbp | Exon Deletion | | mouse |
| Fkbp11tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Fkbp11tm213554(L1L2_Bact_P) | Reporter-tagged deletion allele (with selection cassette) | | targeting vector |
| Fkbp11tm446430(L1L2_GT1_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |