Fmc1 | formation of mitochondrial complex V assembly factor 1

GeneMGI:1913367Synonyms: 1110001J03Rik

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Growth/size/body region Nervous system Vision/eye Behavior/neurological Skeleton Cardiovascular system Mortality/aging Craniofacial

12 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues

Phenotypes

abnormal tooth morphology1 supporting datasetFmc1tm1b(EUCOMM)WtsiheterozygoteEarly adult4.03x10-5 
unresponsive to tactile stimuli1 supporting datasetFmc1tm1b(EUCOMM)WtsihomozygoteE18.5N/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsFmc1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
unresponsive to tactile stimuli1 supporting datasetFmc1tm1b(EUCOMM)WtsiheterozygoteE18.5N/A * 
abnormal brain morphology1 supporting datasetFmc1tm1b(EUCOMM)WtsiheterozygoteEarly adultN/A * 
abnormal retina vasculature morphology1 supporting datasetFmc1tm1b(EUCOMM)WtsiheterozygoteEarly adult2.72x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fmc1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Fmc1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Fmc1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Fmc1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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