Tspan13 | tetraspanin 13
Physiological systems
17 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Adipose tissue Nervous system Behavior/neurological Skeleton
11 No significant impact
7 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal behavior | 1 supporting dataset | Tspan13em1(IMPC)Kmpc | homozygote | Early adult | 8.52x10-7 | ||
| decreased prepulse inhibition | 3 supporting datasets | Tspan13em1(IMPC)Kmpc | homozygote | Early adult | 5.41x10-6 | ||
| increased total body fat amount | 1 supporting dataset | Tspan13em1(IMPC)Kmpc | homozygote | Early adult | 8.91x10-6 | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Tspan13em1(IMPC)Kmpc | homozygote | Early adult | 7.42x10-5 | ||
| decreased thigmotaxis | 2 supporting datasets | Tspan13em1(IMPC)Kmpc | homozygote | Late adult | 8.43x10-9 | ||
| abnormal vibrissa morphology | 1 supporting dataset | Tspan13em1(IMPC)Kmpc | homozygote | Late adult | 4.19x10-7 | ||
| decreased bone mineral density | 1 supporting dataset | Tspan13em1(IMPC)Kmpc | homozygote | Early adult | 9.71x10-6 | ||
| abnormal behavior | 1 supporting dataset | Tspan13em1(IMPC)Kmpc | homozygote | Late adult | 8.43x10-9 | ||
| decreased thigmotaxis | 2 supporting datasets | Tspan13em1(IMPC)Kmpc | homozygote | Early adult | 8.52x10-7 | ||
| decreased bone mineral content | 2 supporting datasets | Tspan13em1(IMPC)Kmpc | homozygote | Early adult | 7.96x10-8 |
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Human diseases caused by Tspan13 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Tspan13.
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| Tspan13em1(IMPC)Kmpc | Indel | | mouse |
| Tspan13em1Llp | Intra-exon deletion | | mouse |
| Tspan13tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Tspan13tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |