Ube2d3 | ubiquitin-conjugating enzyme E2D 3

GeneMGI:1913355Synonyms: 9430029A22Rik, 1100001F19Rik

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Growth/size/body region Vision/eye Behavior/neurological Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	3 supporting datasets	Ube2d3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	7.61x10^-6
decreased bone mineral content	2 supporting datasets	Ube2d3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.16x10^-8
abnormal retina morphology	1 supporting dataset	Ube2d3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.37x10^-5
decreased lean body mass	1 supporting dataset	Ube2d3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.43x10^-5
decreased bone mineral density	1 supporting dataset	Ube2d3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.85x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ube2d3.

Associated images

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Histopathology

There is no histopathology data found for Ube2d3.

IMPC related publications

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External links

No external links available for Ube2d3.

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*Ube2d3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ube2d3^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ube2d3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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