Ypel3 | yippee like 3

GeneMGI:1913340Synonyms: 1190001G19Rik, 0610043B10Rik, +1 more

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Limbs/digits/tail Hearing/vestibular/ear Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

12 No significant impact

3 Not tested

Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

increased vertical activity1 supporting datasetYpel3tm1.1(KOMP)VlcghomozygoteEarly adult2.98x10-11 
short tibia1 supporting datasetYpel3tm1.1(KOMP)VlcghomozygoteEarly adult1.43x10-5 
increased mean corpuscular volume1 supporting datasetYpel3tm1.1(KOMP)VlcghomozygoteEarly adult1.01x10-5 
decreased body length1 supporting datasetYpel3tm1.1(KOMP)VlcghomozygoteEarly adult1.75x10-8 
abnormal startle reflex1 supporting datasetYpel3tm1.1(KOMP)VlcghomozygoteEarly adult2.21x10-5 
hyperactivity1 supporting datasetYpel3tm1.1(KOMP)VlcghomozygoteEarly adult7.58x10-6 
eye hemorrhage1 supporting datasetYpel3tm1.1(KOMP)VlcghomozygoteEarly adult3.07x10-9 
abnormal auditory brainstem response1 supporting datasetYpel3tm1.1(KOMP)VlcghomozygoteEarly adult3.73x10-6 
decreased startle reflex1 supporting datasetYpel3tm1.1(KOMP)VlcghomozygoteEarly adult4.63x10-5 
increased circulating alkaline phosphatase level1 supporting datasetYpel3tm1.1(KOMP)VlcghomozygoteEarly adult8.04x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ypel3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Ypel3tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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