Cystm1 | cysteine-rich transmembrane module containing 1

GeneMGI:1913310Synonyms: 0610010O12Rik

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hyperactivity	2 supporting datasets	Cystm1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.94x10^-5
decreased thigmotaxis	2 supporting datasets	Cystm1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.58x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Cystm1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.88x10^-5
abnormal behavior	1 supporting dataset	Cystm1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.58x10^-6
abnormal lens morphology	2 supporting datasets	Cystm1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.43x10^-7
increased total body fat amount	2 supporting datasets	Cystm1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.02x10^-7
decreased lean body mass	2 supporting datasets	Cystm1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.04x10^-6
decreased exploration in new environment	1 supporting dataset	Cystm1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.21x10^-13
increased leukocyte cell number	1 supporting dataset	Cystm1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.31x10^-6
decreased food intake	1 supporting dataset	Cystm1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.67x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cystm1.

Associated images

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Histopathology

There is no histopathology data found for Cystm1.

IMPC related publications

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External links

No external links available for Cystm1.

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*Cystm1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Cystm1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cystm1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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