Cndp2 | CNDP dipeptidase 2

GeneMGI:1913304Synonyms: 0610010E05Rik, Pep1, +3 more

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Vision/eye Liver/biliary system Behavior/neurological Cardiovascular system

11 No significant impact

4 Not tested

Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

anophthalmia1 supporting datasetCndp2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetCndp2em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal liver morphology1 supporting datasetCndp2em1(IMPC)MbphomozygoteLate adultN/A * 
enlarged heart1 supporting datasetCndp2em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal eye morphology1 supporting datasetCndp2em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetCndp2em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetCndp2em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal skin morphology1 supporting datasetCndp2em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal testis morphology1 supporting datasetCndp2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal pancreas morphology1 supporting datasetCndp2em1(IMPC)MbphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Cndp2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Cndp2em1(IMPC)MbpExon Deletionmouse
Cndp2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cndp2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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