Ndufb5 | NADH:ubiquinone oxidoreductase subunit B5
Physiological systems
17 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Embryo Growth/size/body region Limbs/digits/tail Nervous system Mortality/aging Cardiovascular system
11 No significant impact
7 Not tested
Data collections
Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal neural tube morphology | 1 supporting dataset | Ndufb5em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal embryo turning | 1 supporting dataset | Ndufb5em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Ndufb5em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal allantois morphology | 1 supporting dataset | Ndufb5em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Ndufb5em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| abnormal tail bud morphology | 1 supporting dataset | Ndufb5em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Ndufb5em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Ndufb5em1(IMPC)Bay | heterozygote | E9.5 | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Ndufb5em1(IMPC)Bay | homozygote | E12.5 | N/A * | ||
| abnormal neural tube closure | 1 supporting dataset | Ndufb5em1(IMPC)Bay | homozygote | E9.5 | N/A * |
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External links
No external links available for Ndufb5.
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| Ndufb5em1(IMPC)Bay | Exon Deletion | | mouse |
| Ndufb5tm402102(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |