Carm1 | coactivator-associated arginine methyltransferase 1
Physiological systems
16 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Immune system Hematopoietic system Mortality/aging
13 No significant impact
8 Not tested
Data collections
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Carm1tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased lymphocyte cell number | 1 supporting dataset | Carm1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.91x10-5 |
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Human diseases caused by Carm1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Carm1.
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| Carm1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Carm1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Carm1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |